Tá na príomh-pharaiméadair a dhéanann difear do lyophilization na n-ábhar a shórtáil na monaróirí lyophilizer, go príomha lena n-áirítear 4: teocht eutectic, teocht eutectic, teocht collapse, agus teocht trasdula gloine.
The eutectic temperature refers to the temperature at which the moisture in the material is completely frozen into ice crystals. The principle of vacuum freeze-drying technology is the process of directly sublimating water from a solid state to a gaseous state without going through the liquid state. In this process, only two phases are transformed, that is, the solid state is converted into a gaseous state.
If the material is not completely frozen and some liquid material is retained during the freeze-drying and pre-freezing process, the phenomenon of "bubbling" will occur in the sublimation drying stage, that is, the boiling phenomenon of the liquid material under low pressure. The material is reconstituted again, the internal structure is not uniform, and some materials are sticky, which eventually leads to poor resolubility of the product. Therefore, in the pre-freezing stage, the temperature should be lowered below the eutectic temperature, and the moisture in the material should be completely frozen into ice crystals without the existence of liquid materials.
Tugtar an pointe eutectic freisin ar an teocht eutectic. Tá pointe leá seasta ag uisce, ach ní dhéanann an réiteach. De ghnáth ní leá an réiteach tar éis reo ag teocht sheasta, ach de réir mar a mhéadaíonn an teocht de réir a chéile, laghdaítear méid na criostail de réir a chéile. , go dtí go bhfuil an soladach deiridh leáite go hiomlán. An leáphointe a thugtar ar an teocht ag a bhfeictear leacht nuair a thosaíonn an leá. Maidir le tuaslagán, is é an leáphointe coitianta atá ag an tuaslagáit agus an tuaslagóir. Tugtar an teocht eutectic ar an teocht seo.
Is í an teocht tite, ar a dtugtar an teocht tite freisin, do roinnt ábhar reoite-triomaithe. Nuair a thagann méadú de réir a chéile ar theocht an ábhair thirim reoite, laghdaítear a righin de réir a chéile. Nuair a shroicheann an teocht luach criticiúil áirithe, ní leor a rigidity chun struchtúr tríthoiseach an ábhair a chothabháil, rud a fhágann go dtosóidh an t-ábhar ag titim as a chéile. Tugtar an t-ábhar ar an teocht chriticiúil seo. an teocht titim.
Tagraíonn an teocht trasdula gloine don teocht trasdula gloine d'uastiúchan reoite an ábhair. Chomh maith le foirmiú an ábhair, tá dlúthbhaint ag an teocht trasdula gloine leis an struchtúr, an teocht réamh-reo, agus luas an ábhair.
